Carlisle United are 17/4 to claim their first home win since New Year's Day against high-flying Barnsley.
Those odds are offered by Bet365 as the Cumbrians face the Tykes at Brunton Park.
Paul Simpson's Carlisle, are ten defeats in 11, are desperate for a better night in League One.
A Blues win against Neill Collins' fifth-placed visitors is also priced 7/2 by 888Sport and 10/3 by Betfred.
Barnsley are odds-on to prevail on their first visit to Brunton Park since 1985.
An away win is 7/10 with Betfair and 4/6 with BetVictor.
The draw is 3/1.
Luke Armstrong got the opener when the sides last met in January - and also hit the first goal for Carlisle at Charlton Athletic on Saturday.
The frontman is 9/1 to repeat the feat tonight and claim his first Brunton Park goal in the process.
Barnsley's 17-goal marksman Devante Cole is favourite for the opener at 4/1, with ex-Carlisle man Sam Cosgrove 11/2.
For the Blues, Jack Diamond is 12/1 to strike first, with Jordan Gibson also 12/1.
Longer shots include Taylor Charters at 25/1, Harrison Neal at 33/1 and Dylan McGeouch at 50/1.
Barnsley first-scorer prices also include John McAtee at 15/2, Adam Phillips at 9/1, Nicky Cadden at 14/1 and Luca Connell at 16/1.
Cole is 45/1 for a hat-trick with Armstrong 300/1 for a Blues treble.
These sides' last meeting at Brunton Park some 39 years ago was a 1-1 draw and a repeat of that scoreline this evening is 13/2.
If you fancy a 2-1 Carlisle win, odds of 16/1 are available.
A 2-0 away win is priced 15/2.
Harry Lewis impressed in goal for United on Saturday and a clean sheet by the keeper tonight is 5/1.
Carlisle are 2/1 to force the most corners in the game, Barnsley 3/4.
Source: Oddschecker.
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